PANCREATIC CANCER METASTATIC

This early-phase trial tests whether adding the cholesterol-lowering drug pitavastatin to standard chemotherapy (gemcitabine and nab-paclitaxel) can safely help control advanced pancreatic cancer. About 18 adults whose cancer has not worsened on initial chemo will receive the com…

This study tests a new drug called TNG462, given with other cancer medicines, for people with pancreatic or lung cancer that has a specific genetic change (MTAP loss). The goal is to find safe doses and see if the combination shrinks tumors. About 183 adults with advanced cancer …

This study tests whether adding the experimental drug atebimetinib to standard chemotherapy helps people with metastatic pancreatic cancer live longer. About 510 adults who have not had prior treatment will be randomly assigned to receive either the new combination or standard ch…

This study tests whether adding a new type of targeted nanocell therapy to standard chemotherapy can help people with metastatic pancreatic cancer live longer. The nanocells are designed to deliver a powerful drug directly to cancer cells while also boosting the immune system. Ab…

This study tests a new treatment called EBNK-001, which uses donor natural killer (NK) cells to fight advanced solid tumors. About 83 adults with cancers like lung, breast, or colorectal cancer that have not responded to standard treatments will receive the NK cells along with ch…

This study is for people with advanced or metastatic gastrointestinal cancers, including anal and pancreatic cancers. Researchers are testing a combination of two drugs, pelareorep and atezolizumab, to see if they are safe and can shrink tumors or slow disease growth. About 122 p…

This study tests a new drug called daraxonrasib, either alone or with standard chemotherapy, for people with metastatic pancreatic cancer that has spread. About 900 adults with a RAS gene mutation will be randomly assigned to one of three treatment groups. The goal is to see if t…

This study tests a new chemotherapy combination (paclitaxel polymeric micelles plus gemcitabine) against the current standard treatment for metastatic pancreatic cancer. About 416 adults with advanced pancreatic cancer who have not had prior treatment will take part. The goal is …

This study tests whether adding acupuncture to standard anti-nausea medicine can better control nausea caused by chemotherapy. About 90 adults with various cancers who still feel sick despite medication will either receive acupuncture plus medicine or medicine alone. Researchers …