PANCREATIC CANCER METASTATIC

This study is testing whether a new oral drug called TNG462 is safe and effective when combined with other cancer drugs for people with advanced pancreatic or non-small cell lung cancer. The trial will involve about 183 adults whose cancers have specific genetic changes (MTAP los…

This study is testing whether a new drug called daraxonrasib, given alone or with standard chemotherapy, works better than chemotherapy alone for people with advanced pancreatic cancer that has spread. About 900 participants will be randomly assigned to receive one of three treat…

This study is testing whether adding a new oral drug called narmafotinib to a standard chemotherapy regimen (mFOLFIRINOX) is safe and effective for people with metastatic pancreatic cancer. The first part finds a safe dose, and the second part tests two doses in more people to pi…

This study is testing whether adding a new experimental treatment to standard chemotherapy helps people with advanced pancreatic cancer that has worsened after initial therapy. The experimental treatment uses tiny 'nanocells' designed to deliver chemotherapy directly to cancer ce…

This study is testing a new type of treatment called EBNK-001, which uses donated immune cells (Natural Killer cells) to fight cancer. It is for adults with advanced solid tumors that have grown or returned after standard treatments. The main goals are to find a safe dose and see…

This study is testing a new two-part treatment for people with advanced or spreading cancers of the digestive system, like pancreatic or anal cancer. The treatment combines an engineered virus (pelareorep) with an immunotherapy drug (atezolizumab). Researchers want to see if this…

This study is testing whether a new formulation of paclitaxel chemotherapy (delivered in tiny particles called micelles) works better than the current standard treatment for metastatic pancreatic cancer. About 416 adults with newly diagnosed advanced pancreatic cancer will receiv…

This study is testing whether adding acupuncture to standard anti-nausea medicine helps reduce nausea better for cancer patients undergoing chemotherapy. It will involve 90 patients who are already experiencing nausea despite taking their prescribed anti-sickness drugs. Participa…