New pill plus chemo aims to tackle tough pancreatic cancer
NCT ID NCT07562152
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This Phase 3 trial tests whether adding an experimental oral drug called atebimetinib to a modified chemotherapy regimen helps people with metastatic pancreatic cancer live longer. About 510 adults who have not had prior treatment will receive either the new combination or standard chemotherapy. The study is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
atebimetinib (an experimental oral drug) combined with gemcitabine and nab-paclitaxel chemotherapy
What this could lead to
If successful, this could offer a new first-line treatment option that extends survival for people with metastatic pancreatic cancer.
What could go wrong
This is an early-stage Phase 3 trial, so results are not guaranteed. Adding a targeted drug to chemo may increase side effects without improving outcomes.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Blue Ridge Cancer Care
RECRUITINGBlacksburg, Virginia, 24060, United States
Contact Email: •••••@•••••
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Calvary Mater Newcastle
RECRUITINGWaratah, New South Wales, 2298, Australia
Contact
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City of Hope
RECRUITINGPhoenix, Arizona, 85338, United States
Contact Email: •••••@•••••
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City of Hope
RECRUITINGDuarte, California, 91010, United States
Contact Email: •••••@•••••
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City of Hope
RECRUITINGChicago, Illinois, 60099, United States
Contact Email: •••••@•••••
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Comprehensive Cancer Centers
RECRUITINGLas Vegas, Nevada, 89169, United States
Contact Email: •••••@•••••
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Icon Cancer Centre - Chermside
RECRUITINGChermside, Queensland, 4032, Australia
Contact
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Illinois Cancer Specialists
RECRUITINGArlington Heights, Illinois, 60005, United States
Contact Email: •••••@•••••
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Missouri Cancer Associates
RECRUITINGColumbia, Missouri, 65201, United States
Contact Email: •••••@•••••
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
Contact Email: •••••@•••••
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Northwest Cancer Specialists
RECRUITINGVancouver, Washington, 98684, United States
Contact Email: •••••@•••••
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OSF Medical Center
RECRUITINGPeoria, Illinois, 61603, United States
Contact Email: •••••@•••••
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Piedmont Healthcare
RECRUITINGAtlanta, Georgia, 30318, United States
Contact
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Regional Cancer Care
RECRUITINGBelleville, New Jersey, 07109, United States
Contact Email: •••••@•••••
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Sarah Cannon Research Institute
RECRUITINGNashville, Tennessee, 37203, United States
Contact Email: •••••@•••••
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Taylor Cancer Research Center
RECRUITINGMaumee, Ohio, 43537, United States
Contact Email: •••••@•••••
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Texas Oncology - San Antonio
RECRUITINGSan Antonio, Texas, 78240, United States
Contact
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Texas Oncology Gulf Coast
RECRUITINGWebster, Texas, 77598, United States
Contact Email: •••••@•••••
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Thomas Jefferson University
RECRUITINGPhiladelphia, Pennsylvania, 19107, United States
Contact Email: •••••@•••••