New hope for Hard-to-Treat cancers: experimental drug enters human trials
NCT ID NCT04900818
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tests an experimental drug called TJ033721 (givastomig) in people with advanced or metastatic solid tumors that have stopped responding to standard treatments. The main goals are to check the drug's safety, find the right dose, and see how the body processes it. About 330 participants will receive the drug alone or in combination with other therapies.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for ADVANCED CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Email: •••••@•••••
Locations
-
Beijing Cancer Hospital
RECRUITINGBeijing, Beijing Municipality, 100142, China
-
Carolina BioOncology Institute
COMPLETEDHuntersville, North Carolina, 28078, United States
-
HARBIN Medical University Cancer Hospital
COMPLETEDHarbin, Heilongjiang, 150086, China
-
Henan Cancer Hospital
COMPLETEDZhengzhou, Henan, 45003, China
-
Horizon Oncology Research, LLC.
COMPLETEDLayfayette, Indiana, 47905, United States
-
Hubei Cancer Hospital
COMPLETEDWuhan, Hubei, 430079, China
-
Mary Crowley Cancer Research
COMPLETEDDallas, Texas, 75230, United States
-
Mass General Hospital
RECRUITINGBoston, Massachusetts, 02114, United States
-
Memorial Sloan Kettering Cancer Center
RECRUITINGNew York, New York, 10065, United States
-
NYU Langone
RECRUITINGNew York, New York, 10016, United States
-
Rutgers Cancer Institute of New Jersey
COMPLETEDNew Brunswick, New Jersey, 08901, United States
-
Sir Run Run Shaw Hospital, Zhejiang University School of Medicine
COMPLETEDHangzhou, Zhejiang, 3110020, China
-
Sixth Affiliated Hospital, Sun Yat-sen University
ACTIVE_NOT_RECRUITINGGuangzhou, Guangdong, 510655, China
-
Stern Center for Cancer Clinical Trials and Research
RECRUITINGOrange, California, 92868, United States
-
The First Hospital of China Medical University
COMPLETEDShenyang, Liaoning, 110499, China
-
The Second Hospital of Anhui Medical University
WITHDRAWNHefei, Anhui, 230601, China
-
Tianjin Medical University Cancer Institute and Hospital
COMPLETEDTianjin, Tianjin Municipality, 300060, China
-
UCHealth Cancer Care - Anschutz Medical Campus
RECRUITINGAurora, Colorado, 80045, United States
-
UW Carbone Cancer Center
RECRUITINGMadison, Wisconsin, 53705, United States
-
Vanderbilt-Ingram Cancer Center
COMPLETEDNashville, Tennessee, 37232, United States
-
Zhongshan Hospital, Fudan University
COMPLETEDShanghai, Shanghai Municipality, 200032, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can AI-Guided home training boost recovery from gastric cancer surgery?
- Can a new drug shield nerves from Chemotherapy's side effects?
- Can a new drug combo revive Immunotherapy's power against resistant tumors?
- Can a Tumor's DNA guide better cancer care for kids?
- Can a new infusion drug shrink Hard-to-Treat tumors?
- Could a vaccine help fight Hard-to-Treat cancers?