GASTROESOPHAGEAL JUNCTION CARCINOMA

This study is testing whether a new, step-by-step dosing guide called the PAGODA algorithm can help prevent unplanned delays in FOLFOX chemotherapy for people with gastrointestinal cancers. About 420 participants will be randomly assigned to have their chemotherapy doses adjusted…

This study is testing if adding an experimental drug called givastomig to standard immunotherapy and chemotherapy works better for controlling advanced stomach or esophageal cancer. About 180 adults whose cancer has spread and who have not yet received treatment for their advance…

This is a first-in-human study to test the safety and find the right dose of a new drug called TJ033721 (givastomig) for people with advanced or metastatic solid tumors. It will enroll about 330 patients whose cancer has progressed despite standard treatments or who have no other…

This study is testing whether adding a common antifungal drug, itraconazole, to standard chemotherapy and radiation can help eliminate more cancer before surgery for esophageal cancer. Researchers believe the drug may block cancer growth pathways and make tumors more sensitive to…

This study is testing whether cancer patients prefer to receive their standard drug treatments at home instead of in a clinic. Researchers want to see if home-based care reduces the burden of travel and improves treatment satisfaction and quality of life for patients. A specializ…