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Can a heat probe through an endoscope treat pancreatic lesions?

NCT ID NCT07737171

Recruiting now Disease control Sponsor: The University of Texas Health Science Center, Houston Source: ClinicalTrials.gov ↗

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This study tests whether a procedure called endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) can safely treat pancreatic lesions. The approach uses a special endoscope to deliver heat energy directly to the lesion. Researchers will enroll 60 people with pre-malignant or malignant pancreatic lesions to assess technical success and short-term complications.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Endoscopic ultrasound-guided radiofrequency ablation (RFA) — a procedure that uses a special endoscope to deliver heat energy to pancreatic lesions
What this could lead to
If successful, this approach could offer a less invasive treatment option for pancreatic lesions, potentially reducing the need for surgery.
What could go wrong
This is a small, early registry study (60 participants) focused on safety and technical success, not yet proving long-term benefit. Risks include pancreatitis, bleeding, and other complications.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic neoplasm precancerous condition

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC CANCER

Contacts and locations

Locations

  • The University of Texas Health Science Center at Houston

    RECRUITING

    Houston, Texas, 77030, United States

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