Microchip implanted in pancreatic tumors could personalize chemo choices

NCT ID NCT07254091

Recruiting now Knowledge-focused Sponsor: Northwell Health Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This pilot study tests a tiny implantable device that delivers microdoses of several chemotherapy drugs directly into pancreatic tumors during surgery. The device is removed after four hours, and the surrounding tissue is analyzed to see which drugs worked best. Ten adults with pancreatic cancer who are already scheduled for surgery will take part. The main goal is to check safety, but researchers also hope to learn whether this approach can guide personalized treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: microdevice containing microdoses of chemotherapy drugs (doxorubicin, gemcitabine, paclitaxel, 5-fluorouracil, oxaliplatin, irinotecan)
What this could lead to: If successful, this device could help doctors quickly identify which chemotherapy drugs work best for each patient's pancreatic cancer, leading to more personalized treatment.
What could go wrong: This is a very early safety study with only 10 participants. The device is experimental and may not provide useful drug response data. There is a risk of complications from implantation and removal.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC CANCER

Contacts and locations

Locations

Zuckerberg Cancer Center
RECRUITING

New Hyde Park, New York, 11040, United States

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