Engineered immune cells take aim at Hard-to-Treat cancers
NCT ID NCT02830724
First seen Jun 27, 2026 · Last updated Aug 14, 2026 · Updated 5 times
Summary
This study tests a new treatment for adults with certain cancers (pancreatic, kidney, breast, melanoma, or ovarian) that have a protein called CD70. Doctors take a sample of your blood, modify your white blood cells in a lab to recognize and attack CD70, and then give them back to you. The goal is to see if this gene therapy can safely shrink tumors. Participants will receive chemotherapy before the cell infusion and must take antibiotics for six months after.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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