RENAL CELL CANCER

This study tests a new cancer vaccine called Modi-1 in 168 people with advanced breast, head & neck, ovarian, or kidney cancer. The vaccine is designed to help the immune system recognize and attack cancer cells. Some participants will receive the vaccine alone, while others will…

This study tests a new treatment for people with certain cancers (pancreatic, kidney, breast, melanoma, or ovarian) that have a protein called CD70. Doctors take a sample of your blood, remove white blood cells, modify them in the lab to recognize and attack CD70, and then give t…

This study tests an experimental oral drug called Alintegimod combined with standard immunotherapies (ipilimumab and nivolumab) in people with advanced solid tumors like melanoma, lung, kidney, or liver cancer who have already tried other treatments. The goal is to see if the com…

This study looks at how older adults (70+) with advanced kidney cancer handle a combination of two drugs, cabozantinib and nivolumab. Researchers want to see what doses work best and how often side effects cause treatment breaks. The goal is to improve treatment for this age grou…

This study looks at how well the drug vorolanib works for people with advanced kidney cancer that has spread or cannot be removed by surgery. It is for patients who need a second treatment after the first one stopped working. Researchers will track how long patients live without …

This study tests whether special ultrasound scans (CEUS and super-resolution imaging) can predict how well the kidneys will work after partial or complete kidney removal for cancer. About 285 adults will get these scans before and after surgery, plus blood and urine tests, and be…