New vaccine aims to train immune system against four tough cancers

NCT ID NCT05329532

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This study tests a new cancer vaccine called Modi-1 in 168 people with advanced breast, head & neck, ovarian, or kidney cancer. The vaccine is designed to help the immune system recognize and attack cancer cells. Some participants receive the vaccine alone, while others get it combined with standard immunotherapy drugs. The goal is to check safety and see if the vaccine shrinks tumors or delays cancer growth.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Addenbrooke's Hospital, Cambridge University Hospitals

    RECRUITING

    Cambridge, United Kingdom

    Contact Phone: •••-•••-••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Belfast City Hospital

    RECRUITING

    Belfast, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Brighton and Sussex University Hospital

    ACTIVE_NOT_RECRUITING

    Brighton, Default, United Kingdom

  • Christie NHS Foundation Trust

    RECRUITING

    Manchester, Default, United Kingdom

    Contact Email: •••••@•••••

  • Edinburgh Cancer Centre (NHS Lothian)

    RECRUITING

    Edinburgh, Default, United Kingdom

    Contact Email: •••••@•••••

  • Imperial College Healthcare NHS Trust

    ACTIVE_NOT_RECRUITING

    London, Default, United Kingdom

  • Lancashire Teaching Hospitals NHS Foundation Trust

    RECRUITING

    Preston, Default, United Kingdom

    Contact Email: •••••@•••••

  • Mount Vernon

    RECRUITING

    London, Default, United Kingdom

    Contact Email: •••••@•••••

  • Nottingham University Hospitals Cancer Centre

    RECRUITING

    Nottingham, Default, United Kingdom

    Contact Email: •••••@•••••

  • Royal Surrey NHS Foundation

    RECRUITING

    Guildford, Default, United Kingdom

    Contact Email: •••••@•••••

  • Sheffield Teaching Hospital NHS Foundation Trust

    RECRUITING

    Sheffield, Default, United Kingdom

    Contact Email: •••••@•••••

  • The Clatterbridge Cancer Centre NHS Foundation Trust

    RECRUITING

    Liverpool, CH63 4JY, United Kingdom

    Contact Email: •••••@•••••

  • The Royal Marsden NHS Foundation Trust

    NOT_YET_RECRUITING

    Sutton, Default, United Kingdom

    Contact Email: •••••@•••••

  • Torbay and South Devon NHS Foundation Trust

    RECRUITING

    Torquay, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University College London Hospital NHS Foundation Trust

    RECRUITING

    London, Default, United Kingdom

    Contact Email: •••••@•••••

  • Velindre Cancer Centre

    RECRUITING

    Cardiff, Default, United Kingdom

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.