Could blood from a cancer's own vein reveal more tumor DNA?

NCT ID NCT05497531

First seen Feb 26, 2026 · Last updated Jun 19, 2026 · Updated 16 times

Summary

This pilot study compares two ways of collecting blood to find circulating tumor DNA (ctDNA) in people with liver or pancreatic cancers. Researchers will take blood from a standard arm vein and also from the vein that drains directly from the tumor during a biopsy. The goal is to see if the tumor-draining vein sample contains more or different ctDNA. Only 15 participants are needed for this early-stage study.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

Locations

  • Chao Family Comprehensive Cancer Center, University of California, Irvine

    RECRUITING

    Orange, California, 92868, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could lead to a more sensitive way to detect tumor DNA, potentially improving cancer monitoring and treatment decisions.

What could go wrong

This is a very small pilot study (15 people) and only tests a blood collection method, not a treatment. It may not show a meaningful difference or be practical for wider use.

Conditions

The condition(s) this trial relates to.

carcinoma of the ampulla of vater cholangiocarcinoma exocrine pancreatic carcinoma hepatobiliary neoplasm hepatocellular carcinoma malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.