New 'Alpha Bullets' radiation device targets tough pancreatic tumors
NCT ID NCT06698458
First seen Nov 01, 2025 · Last updated Jun 21, 2026 · Updated 41 times
Summary
This study tests a new device called DaRT that delivers a special type of radiation directly into pancreatic tumors. It is being combined with standard chemotherapy in 30 people with advanced or metastatic pancreatic cancer. The main goal is to see if the combination is safe, and also to check if it helps control pain and shrink tumors.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Advent Health Cancer Institute
NOT_YET_RECRUITINGOrlando, Florida, 32804, United States
Contact Email: •••••@•••••
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Banner MD Anderson Cancer Center
RECRUITINGGilbert, Arizona, 85234, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Bassett Healthcare Network
RECRUITINGCooperstown, New York, 13326, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Baylor College of Medicine
RECRUITINGHouston, Texas, 77054, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Cedars-Sinai
NOT_YET_RECRUITINGLos Angeles, California, 90048, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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City of Hope
NOT_YET_RECRUITINGGoodyear, Arizona, 85338, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Email: •••••@•••••
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Emory University
RECRUITINGAtlanta, Georgia, 30308, United States
Contact
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Hadassah Ein Kerem
RECRUITINGJerusalem, Israel
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Honor Health
RECRUITINGScottsdale, Arizona, 85258, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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Jewish General Hospital
RECRUITINGMontreal, Quebec, Canada
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Lenox hill Hospital
NOT_YET_RECRUITINGNew York, New York, 10075, United States
Contact Email: •••••@•••••
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Montefiore Medical Center
RECRUITINGThe Bronx, New York, 10467, United States
Contact Email: •••••@•••••
Contact Email: •••••@•••••
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NYU Langone Health
RECRUITINGNew York, New York, 10016, United States
Contact Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Texas Oncology
NOT_YET_RECRUITINGHouston, Texas, 75251, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University Cancer and Diagnostic
RECRUITINGHouston, Texas, 77089, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Diffusing Alpha Radiation Emitters Therapy (DaRT) device
What this could lead to
If it works, this could offer a new way to control pancreatic tumors and improve survival when used with standard chemotherapy.
What could go wrong
This is an early safety study with only 30 participants, so results may not apply to everyone. The procedure is invasive and side effects are unknown.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.