Radioactive 'Seeds' take on pancreatic cancer

NCT ID NCT06755359

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new approach for locally advanced pancreatic cancer: tiny radioactive sources placed directly into the tumor to deliver alpha radiation. The treatment is combined with standard chemotherapy. The main goal is to check safety in 40 participants, but researchers will also look at whether it shrinks tumors and improves survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Diffusing Alpha Radiation Emitters Therapy (DaRT) - radioactive sources inserted into the tumor

What this could lead to

If successful, this could offer a new treatment option for locally advanced pancreatic cancer by combining targeted radiation with chemotherapy to control the disease.

What could go wrong

This is an early safety study with only 40 participants, so effectiveness is not yet proven. The procedure involves inserting radioactive sources into the tumor, which carries risks like infection or damage to nearby organs.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU Grenoble Alpes

    RECRUITING

    Grenoble, France

    Contact Email: •••••@•••••

  • CHU Poitiers

    NOT_YET_RECRUITING

    Poitiers, France

  • CHU Poitiers

    NOT_YET_RECRUITING

    Poitiers, France

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • CHU de Bordeaux

    NOT_YET_RECRUITING

    Bordeaux, France

  • CHU de Bordeaux

    NOT_YET_RECRUITING

    Bordeaux, France

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Centre Georges François Leclerc Dijon

    NOT_YET_RECRUITING

    Dijon, France

  • Centre Georges François Leclerc Dijon

    NOT_YET_RECRUITING

    Dijon, France

  • Centre Georges François Leclerc Dijon

    NOT_YET_RECRUITING

    Dijon, France

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

    Contact Email: •••••@•••••

  • Centre Jean PERRIN - Clermont-Ferrand

    NOT_YET_RECRUITING

    Clermont-Ferrand, France

    Contact Email: •••••@•••••

  • Gustave Roussy Institute

    NOT_YET_RECRUITING

    Villejuif, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hôpital Privé Mermoz - Lyon

    NOT_YET_RECRUITING

    Lyon, France

    Contact Email: •••••@•••••

  • Marseille

    NOT_YET_RECRUITING

    Marseille, France

    Contact Email: •••••@•••••