Radioactive 'Seeds' take on pancreatic cancer

NCT ID NCT06755359

Recruiting now Disease control Sponsor: Alpha Tau Medical LTD. Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new approach for locally advanced pancreatic cancer: tiny radioactive sources placed directly into the tumor to deliver alpha radiation. The treatment is combined with standard chemotherapy. The main goal is to check safety in 40 participants, but researchers will also look at whether it shrinks tumors and improves survival.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Diffusing Alpha Radiation Emitters Therapy (DaRT) - radioactive sources inserted into the tumor
What this could lead to: If successful, this could offer a new treatment option for locally advanced pancreatic cancer by combining targeted radiation with chemotherapy to control the disease.
What could go wrong: This is an early safety study with only 40 participants, so effectiveness is not yet proven. The procedure involves inserting radioactive sources into the tumor, which carries risks like infection or damage to nearby organs.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for LOCALLY ADVANCED PANCREATIC CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

malignant pancreatic neoplasm pancreatic adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LOCALLY ADVANCED PANCREATIC CANCER PANCREATIC CANCER

Contacts and locations

Locations

CHU Grenoble Alpes
RECRUITING

Grenoble, France
CHU Poitiers
NOT_YET_RECRUITING

Poitiers, France
CHU Poitiers
NOT_YET_RECRUITING

Poitiers, France
CHU de Bordeaux
NOT_YET_RECRUITING

Bordeaux, France
CHU de Bordeaux
NOT_YET_RECRUITING

Bordeaux, France
Centre Georges François Leclerc Dijon
NOT_YET_RECRUITING

Dijon, France
Centre Georges François Leclerc Dijon
NOT_YET_RECRUITING

Dijon, France
Centre Georges François Leclerc Dijon
NOT_YET_RECRUITING

Dijon, France
Centre Jean PERRIN - Clermont-Ferrand
NOT_YET_RECRUITING

Clermont-Ferrand, France
Gustave Roussy Institute
NOT_YET_RECRUITING

Villejuif, France
Hôpital Privé Mermoz - Lyon
NOT_YET_RECRUITING

Lyon, France
Marseille
NOT_YET_RECRUITING

Marseille, France

More trials for these conditions

Other studies related to the condition(s) this trial covers.