Engineered immune cells take on Hard-to-Treat cancers

NCT ID NCT06885697

First seen Jun 27, 2026 · Last updated Aug 12, 2026 · Updated 4 times

Summary

This early-phase study tests a new treatment called TNhYP218 CAR T cells for people with solid tumors that have high levels of a protein called mesothelin, including mesothelioma. Participants' own immune cells are collected, modified in a lab to better attack cancer, and then given back. The goal is to find a safe dose and see if the treatment shrinks tumors.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.