COLONIC NEOPLASMS

This early-stage study is testing a new type of personalized cell therapy for people with advanced solid tumors, including mesothelioma, that have come back or spread after standard treatments. Doctors collect a patient's own immune cells, genetically modify them in a lab to bett…

This study is testing whether adding aerobic exercise during chemotherapy helps people with colon cancer better tolerate their full planned treatment doses. Researchers will compare an exercise program to a general health education program in 219 adults with stage II or III colon…

This large, late-stage trial is testing whether a new immunotherapy drug called dostarlimab, given around the time of surgery, works better than standard chemotherapy for people with a specific type of colon cancer that has a high chance of returning. The study will enroll nearly…

This study looks back at past medical records to see how well and how safely different 'scope' procedures work for removing early cancers and pre-cancers from the digestive tract (like the stomach, colon, and esophagus). It will compare several minimally invasive techniques to se…

This study is testing different ways to help more people in Appalachian communities complete colon cancer screening. Researchers are mailing two types of home test kits (standard and enhanced) and providing support through either phone calls or text messages. The goal is to find …