Simple stool test could revolutionize colon cancer screening

NCT ID NCT00843375

Recruiting now Diagnosis Sponsor: University of Michigan Rogel Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

Colon cancer is common but preventable if caught early. While colonoscopy is the best screening tool, many people can't get one due to cost or time. This study collects stool and blood samples from 1,200 adults to find proteins that signal colon polyps or cancer. The goal is to develop a simpler, accurate test for early detection.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to a non-invasive stool or blood test for early colon cancer detection, making screening more accessible.
What could go wrong: This is an observational study collecting samples, not testing a treatment. The biomarkers may not prove accurate enough to replace colonoscopy.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal adenocarcinoma colorectal adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLONIC NEOPLASMS

Contacts and locations

Locations

Carle Cancer Center
COMPLETED

Urbana, Illinois, 61801, United States
Cedars-Sinai Medical Center
RECRUITING

Los Angeles, California, 90048, United States
Dana Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
Flinders Medical Center
RECRUITING

Adelaide, South Australia, 5001, Australia
Hershey Medical Center
COMPLETED

Hershey, Pennsylvania, 17033, United States
M.D. Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States
NYU Langone Health
RECRUITING

New York, New York, 10016, United States
Oregon Health and Science University
RECRUITING

Portland, Oregon, 97239, United States
St. Michael's Hospital
WITHDRAWN

Toronto, Ontario, Canada
University of Michigan
RECRUITING

Ann Arbor, Michigan, 48109, United States
University of Minnesota
RECRUITING

Minneapolis, Minnesota, 55455, United States
University of North Carolina
COMPLETED

Chapel Hill, North Carolina, 27599, United States
University of Washington
RECRUITING

Seattle, Washington, 98195, United States

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