AI eye on polyps: could a computer match the microscope?

NCT ID NCT07738484

First seen Jul 31, 2026 · Last updated Jul 31, 2026

Summary

This trial tests whether an AI system called GI Genius can help doctors accurately tell apart small colorectal polyps (5 mm or less) during a colonoscopy—identifying which ones are harmless versus those that need monitoring. For each small polyp, doctors first record their own diagnosis, then activate the AI and record a second diagnosis after seeing its assessment. Both are compared to the final pathology report, the gold standard. The study involves about 840 adults undergoing routine colonoscopies at three Canadian centers, with no extra visits or procedures.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
GI Genius CADx module (Medtronic), an AI-assisted computer-aided diagnosis device
What this could lead to
If successful, this AI tool could help doctors accurately identify harmless polyps during colonoscopy, potentially reducing unnecessary lab tests and lowering healthcare costs.
What could go wrong
The AI may not meet the accuracy thresholds needed for clinical use, and its performance could vary across different patient groups and settings. The study is observational, so it does not change patient care.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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