A simple blood draw could spot colorectal cancer early

NCT ID NCT07035691

Recruiting now Diagnosis Sponsor: Queen Mary University of London Source: ClinicalTrials.gov ↗

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This study is testing whether a blood test can accurately identify colorectal cancer or polyps in adults referred for suspected lower GI cancer. Participants provide a blood sample during their routine diagnostic visit, and their results are compared to their final diagnosis. The study also explores patient preferences for blood-based tests versus more invasive procedures like colonoscopy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: A blood test measuring progastrin (hPG80) and transposable elements (TEs)
What this could lead to: If accurate, this blood test could offer a less invasive way to detect colorectal cancer and polyps, potentially reducing the need for colonoscopies.
What could go wrong: This is an observational study, so it won't prove the test works in practice. The biomarkers may not be accurate enough, and results may not apply to all patients.

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Conditions

The condition(s) this trial relates to.

adenoma colorectal adenoma colorectal cancer colorectal carcinoma colorectal neoplasm disease neoplasm polyp

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COLORECTAL ADENOMA COLORECTAL CARCINOMA POLYP

Contacts and locations

Locations

Barts Health NHS Trust
RECRUITING

London, England, E1 2AT, United Kingdom

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