New radiation method may boost immune attack on tumors

NCT ID NCT05837767

Recruiting now Symptom relief Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares a new radiation technique called lattice radiation therapy (LRT) to standard stereotactic body radiation therapy (SBRT) for people with solid tumors that have spread to soft tissues. The goal is to see if LRT shrinks tumors better and helps the immune system fight cancer cells. About 26 adults with advanced breast, lung, gastrointestinal, bladder, kidney, melanoma, or sarcoma cancers will participate.

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Conditions

The condition(s) this trial relates to.

breast ductal adenocarcinoma breast lobular carcinoma Carcinoma, Lobular digestive system cancer digestive system neoplasm invasive ductal breast carcinoma invasive lobular breast carcinoma malignant pancreatic neoplasm melanoma metastatic malignant neoplasm Neoplasm Metastasis non-small cell lung carcinoma pancreatic neoplasm renal cell carcinoma sarcoma soft tissue sarcoma urinary bladder carcinoma Urinary Bladder Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLADDER CANCER GASTROINTESTINAL ADENOCARCINOMA GASTROINTESTINAL CANCER GASTROINTESTINAL SQUAMOUS CELL CANCER INVASIVE DUCTAL BREAST CARCINOMA INVASIVE DUCTAL BREAST CARCINOMA STAGE IV LOBULAR BREAST CARCINOMA LOBULAR BREAST CARCINOMA STAGE IV MELANOMA METASTATIC SOLID TUMOR NON-SMALL CELL LUNG CANCER NSCLC PANCREATIC CANCER RENAL CELL CARCINOMA SARCOMA

Contacts and locations

Locations

Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities)
RECRUITING

Basking Ridge, New Jersey, 07920, United States
Memorial Sloan Kettering Bergen (Limited protocol activities)
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
RECRUITING

New York, New York, 10065, United States
Memorial Sloan Kettering Monmouth (Limited Protocol Activities)
RECRUITING

Middletown, New Jersey, 07748, United States
Memorial Sloan Kettering Nassau (Limited protocol activities)
RECRUITING

Rockville Centre, New York, 11553, United States
Memorial Sloan Kettering Suffolk- Commack (Limited Protocol Activities)
RECRUITING

Commack, New York, 11725, United States
Memorial Sloan Kettering Westchester (All Protocol Activities)
RECRUITING

Harrison, New York, 10604, United States

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