Cancer-Killing virus trial launches for patients out of options

NCT ID NCT06910657

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 1 trial tests IDOV-Immune, a genetically engineered virus designed to infect and destroy cancer cells while boosting the immune system. It is for adults with advanced solid tumors (like colorectal, pancreatic, or lung cancer) that have not responded to standard treatments. Participants receive a single intravenous dose, and researchers will monitor safety, side effects, and any signs of tumor shrinkage.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

IDOV-Immune (a genetically engineered virus that targets and kills cancer cells)

What this could lead to

If this trial succeeds, it could point toward a new treatment option for people with advanced solid tumors that have not responded to standard therapies.

What could go wrong

This is a very early Phase 1 trial with only 78 participants, so it is not yet known if the treatment is safe or effective. There is a risk of side effects from the virus, and the therapy may not shrink tumors.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

adrenal gland cancer adrenal gland neoplasm breast cancer breast neoplasm cervical cancer cervical carcinoma colorectal cancer colorectal neoplasm esophageal cancer Esophageal Neoplasms gastric cancer gastric neoplasm head and neck cancer Head and Neck Neoplasms hepatocellular carcinoma lung cancer lung neoplasm malignant pancreatic neoplasm melanoma neoplasm Neoplasm Metastasis ovarian cancer pancreatic neoplasm prostate cancer renal cell carcinoma sarcoma urinary bladder carcinoma Urinary Bladder Neoplasms Uterine Cervical Neoplasms vaccinia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • MD Anderson Cancer Center

    NOT_YET_RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Royal North Shore Hospital

    NOT_YET_RECRUITING

    Saint Leonards, New South Wales, 2065, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • South Texas Accelerated Research Therapeutics

    RECRUITING

    San Antonio, Texas, 78229, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The Alfred Hospital

    RECRUITING

    Melbourne, Victoria, 3004, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University School of Medicine

    NOT_YET_RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Westmead Hospital

    RECRUITING

    Westmead, New South Wales, 2145, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••