New MRI scan could sharpen cancer detection

NCT ID NCT02421380

Recruiting now Diagnosis Sponsor: Memorial Sloan Kettering Cancer Center Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 22, 2026 · Updated 2 times

Summary

This study is testing whether a new MRI technique using a substance called hyperpolarized pyruvate gives consistent results in people with solid tumors. About 109 participants will have two special MRI scans to see if the images are reproducible. The goal is to improve how doctors see tumor metabolism, not to treat the cancer.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: hyperpolarized pyruvate
What this could lead to: If successful, this could lead to a more reliable way to see tumor metabolism using MRI, helping doctors better understand and monitor cancer.
What could go wrong: This is an early-stage reproducibility study, not a treatment trial. It may not show clear benefits for patients, and the technique might not be widely usable.

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Conditions

The condition(s) this trial relates to.

brain cancer brain neoplasm breast cancer cancer malignant pancreatic neoplasm metastatic malignant neoplasm prostate cancer sarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MALIGNANT SOLID TUMORS

Contacts and locations

Locations

Memorial Sloan Kettering Bergen (Consent only )
RECRUITING

Montvale, New Jersey, 07645, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States

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