Gene test may tame chemo toxicity in pancreatic and colorectal cancers

NCT ID NCT05391126

First seen Jan 07, 2026 · Last updated May 16, 2026 · Updated 22 times

Summary

This study tests whether using a person's genetic makeup to decide the dose of chemotherapy can lower the risk of severe side effects. About 178 adults with colorectal or pancreatic cancer will be randomly assigned to either standard dosing or dosing based on their UGT1A1 gene type. The goal is to see if personalized dosing reduces serious adverse events during the first treatment cycle.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Kentucky

    RECRUITING

    Lexington, Kentucky, 40506, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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