Gene test may cut chemo harm in pancreatic and colon cancer

NCT ID NCT05391126

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether using a person's genetic information to guide chemotherapy dosing can lower the risk of severe side effects. About 178 adults with colorectal or pancreatic cancer will be randomly assigned to either standard dosing or dosing based on their UGT1A1 gene type. The main goal is to see if the gene-guided approach reduces serious side effects during the first treatment cycle.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm malignant pancreatic neoplasm pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Kentucky

    RECRUITING

    Lexington, Kentucky, 40506, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••