New combo therapy targets tough cancers
NCT ID NCT04421820
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called BOLD-100 combined with standard FOLFOX chemotherapy in people with advanced colorectal, pancreatic, stomach, or bile duct cancers that have spread or cannot be removed. The goal is to see if the combination is safe and helps control tumor growth. About 220 adults will take part, first in a small dose-finding group, then in a larger group to measure how well it works.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHOLANGIOCARCINOMA are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Email: •••••@•••••
Locations
-
AOU L. Vanvitelli
NOT_YET_RECRUITINGNaples, Italy
-
Azienda Ospedaliero Universitaria Pisana
NOT_YET_RECRUITINGPisa, Italy
-
Cross Cancer Institue
RECRUITINGEdmonton, Alberta, Canada
-
Early Phase Unit FJD START Madrid
NOT_YET_RECRUITINGMadrid, Spain
-
Fondazione IRCCS "Istituto Nazionale dei Tumori
NOT_YET_RECRUITINGMilan, Italy
-
Hospital 12 de Octubre
NOT_YET_RECRUITINGMadrid, Spain
-
Jewish General Hospital
RECRUITINGMontreal, Quebec, Canada
-
Juravinski Cancer Centre
RECRUITINGHamilton, Ontario, Canada
-
Kangbuk Samsung Hospital
RECRUITINGSeoul, South Korea
-
Mater Miserecordiae University Hospital
RECRUITINGDublin, Ireland
-
McGill University Health Centre Glen Site
RECRUITINGMontreal, Quebec, Canada
-
Moffitt Cancer Center
COMPLETEDTampa, Florida, 33612, United States
-
National Cancer Center
RECRUITINGGoyang, South Korea
-
Princess Margaret Cancer Centre
RECRUITINGToronto, Ontario, Canada
-
Samsung Medical Center
RECRUITINGSeoul, South Korea
-
Seoul National University Hospital
RECRUITINGSeoul, South Korea
-
Severance Hospital - Yonsei University
RECRUITINGSeoul, South Korea
-
St. James Hospital
RECRUITINGDublin, Ireland
-
St. Vincent's University Hospital
RECRUITINGDublin, Ireland
-
The Ottawa Hospital Cancer Centre
RECRUITINGOttawa, Ontario, Canada
-
Universitatsklinikum Bonn
RECRUITINGBonn, Germany
-
University Hospital of Ulm
RECRUITINGUlm, Germany
-
University of California, Los Angeles
COMPLETEDSanta Monica, California, 90095, United States
-
Vall Hebron Institute of Oncology (VHIO)
NOT_YET_RECRUITINGBarcelona, Spain
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a plasma beam stop colon polyps from coming back?
- A stitch in time: could a device make abdominal closure safer?
- Can we predict chemo brain before it happens?
- Your gut bacteria might reveal hidden cancer risk
- Can a smart digital program restore sleep for cancer survivors?
- Can a new infusion drug shrink Hard-to-Treat tumors?