New study gathers key materials to create personalized cell therapies for tough cancers

NCT ID NCT04981119

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This observational study collects tumor tissue and blood cells from 200 people with advanced solid tumors like colorectal, lung, and pancreatic cancers. The goal is to understand how often tumors lose a specific marker (HLA) and to store participants' own T cells for potential future CAR T-cell therapy. No treatment is given in this study—it only gathers information and materials for later research.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this study could help create personalized CAR T-cell therapies for hard-to-treat solid tumors like colorectal, lung, and pancreatic cancers.

What could go wrong

This is an early, observational study that does not test any treatment. It only collects samples for future research, so there is no direct benefit to participants.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cancer colorectal cancer colorectal carcinoma colorectal neoplasm head and neck squamous cell carcinoma kidney cancer malignant mesothelioma malignant pancreatic neoplasm malignant pleural mesothelioma mesothelioma Mesothelioma, Malignant neoplasm non-small cell lung carcinoma ovarian cancer ovarian carcinoma ovarian neoplasm pancreatic neoplasm pleural mesothelioma renal cell carcinoma triple-negative breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Banner Health

    RECRUITING

    Gilbert, Arizona, 85234, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • City of Hope

    COMPLETED

    Duarte, California, 90101, United States

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact Email: •••••@•••••

    Contact

    Contact

  • MD Anderson Cancer Center

    COMPLETED

    Houston, Texas, 77030, United States

  • Massachusetts General Hospital/Dana Farber Cancer Institute

    COMPLETED

    Boston, Massachusetts, 02114, United States

  • Mayo Clinic Hospital

    RECRUITING

    Phoenix, Arizona, 85054, United States

    Contact

    Contact Phone: •••-•••-••••

  • Mayo Clinic Jacksonville

    RECRUITING

    Jacksonville, Florida, 32224, United States

    Contact Email: •••••@•••••

    Contact

  • Mayo Clinic Rochester

    RECRUITING

    Rochester, Minnesota, 55905, United States

    Contact Email: •••••@•••••

    Contact

    Contact

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33136, United States

    Contact

    Contact Email: •••••@•••••

    Contact

  • NYU Langone Medical Center

    RECRUITING

    New York, New York, 10016, United States

    Contact Email: •••••@•••••

    Contact

  • Stanford University

    RECRUITING

    Palo Alto, California, 94304, United States

    Contact Email: •••••@•••••

    Contact

  • The Ohio State University Comprehensive Cancer Center

    RECRUITING

    Columbus, Ohio, 43210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • UCLA Medical Center

    RECRUITING

    Santa Monica, California, 90404, United States

    Contact

    Contact

    Contact Email: •••••@•••••

  • University of California San Diego

    RECRUITING

    La Jolla, California, 92093, United States

    Contact Email: •••••@•••••

    Contact

  • Vanderbilt University Medical Center

    RECRUITING

    Nashville, Tennessee, 37232, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Washington University

    RECRUITING

    St Louis, Missouri, 63110, United States

    Contact Email: •••••@•••••

    Contact