RENAL CELL CARCINOMA (KIDNEY CANCER)

This study looks at whether having patients report their symptoms weekly through a digital app helps doctors make better treatment decisions. It involves 83 adults with advanced kidney cancer who are starting a combination of two drugs (cabozantinib and nivolumab). The goal is to…

This early-stage study tests a new drug called KO-2806 in people with advanced solid tumors that have not responded to standard treatments. The main goals are to check safety and see if the drug can shrink tumors, either alone or combined with other therapies. About 300 adults wi…

This study tests whether adding precise, high-dose radiation (SBRT) to standard drug therapy can help people with kidney cancer that has spread to up to 5 spots live longer without the cancer growing. About 252 adults with kidney cancer will be randomly assigned to receive either…

This study tests a new drug, 177Lu-TLX250, which delivers radiation directly to kidney cancer cells. It is for adults with advanced clear cell renal cell carcinoma that has come back or spread. The trial compares two different doses of the drug to standard single-drug therapy to …

This study looks at whether adding a quick, no-needle CT scan of the belly to the standard lung cancer screening can help find kidney cancer, enlarged blood vessels, and kidney stones early. About 6,200 smokers aged 55-70 will take part. The goal is to see if the extra scan is pr…

This observational study collects tumor tissue and blood cells from 200 adults with advanced solid tumors like colorectal, lung, or pancreatic cancer. The goal is to understand how often tumors lose a specific marker (HLA) and to store participants' own T cells for possible futur…

This study is measuring a protein called Galectin-3 in the blood of 300 people with kidney, bladder, lung, or liver cancer who are starting immunotherapy. The goal is to see if higher levels of this protein are linked to worse treatment outcomes or more side effects. Researchers …

This study looks back at medical records from 4,700 kidney cancer patients treated between 2012 and 2024. The goal is to create a tool that can predict how the disease will progress and help doctors choose the best treatment for each patient. No new drugs or treatments are being …

This study looks at how certain cancer immunotherapies (anti-PD-1 drugs) might affect bone strength. Researchers will measure bone density and blood markers in 25 adults receiving these treatments for cancers like melanoma, lung, or breast cancer. The goal is to understand if the…

This study works with kidney cancer patients and their partners to learn about their fear of the cancer coming back after surgery. Researchers will form a panel to decide the best ways to ask about these fears and test those methods in a small pilot study. The goal is to improve …