New trial aims to boost survival in kidney cancer by combining radiation with drug therapy

NCT ID NCT06726421

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase III trial is testing whether adding a precise type of radiation (SBRT) to standard drug therapy (targeted drugs and/or immunotherapy) can help people with kidney cancer that has spread to up to five spots live longer without the disease getting worse. The study will enroll 252 participants and compare the combination approach to drug therapy alone. Researchers will also track side effects and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Stereotactic body radiotherapy (SBRT) plus standard systemic therapy (targeted drugs and/or immunotherapy)

What this could lead to

If it works, this could show that adding precise radiation to standard drugs helps people with limited kidney cancer spread live longer without progression.

What could go wrong

This is an early-stage Phase III trial with 252 participants, so results may not apply to everyone. Adding radiation may increase side effects without clear benefit.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

kidney cancer renal cell carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Hospital, Chinese Academy of Medical Sciences

    NOT_YET_RECRUITING

    Beijing, 100021, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • Fudan University Shanghai Cancer Center

    RECRUITING

    Shanghai, 200032, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Peking University First Hospital

    RECRUITING

    Beijing, 100034, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Sun Yat-sen University Cancer Center

    RECRUITING

    Guangzhou, Guangdong, 510060, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The First Affiliated Hospital of Wenzhou Medical University

    RECRUITING

    Wenzhou, Zhejiang, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • The First Hospital of Jilin University

    RECRUITING

    Changchun, Jilin, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Union Hospital, Fujian Medical University

    RECRUITING

    Fuzhou, Fujian, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

    RECRUITING

    Wuhan, Hubei, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • West China Hospital, Sichuan University

    RECRUITING

    Chengdu, Sichuan, 610041, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact