New vaccine combo takes on tough cancers

NCT ID NCT06411691

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests a cancer vaccine that targets a common mutated protein (KRAS) combined with two immunotherapy drugs (balstilimab and botensilimab) in people with advanced colorectal or pancreatic cancer that has spread. The goal is to see if the combination can shrink tumors or slow disease progression. About 54 adults whose cancer has not responded to standard chemotherapy will participate.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colonic neoplasm colorectal cancer colorectal neoplasm malignant pancreatic neoplasm pancreatic ductal adenocarcinoma pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sidney Kimmel Comprehensive Cancer Center

    RECRUITING

    Baltimore, Maryland, 21231, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••