Zapping spreading tumors could extend life on current cancer drugs
NCT ID NCT06101277
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study tests whether adding a targeted, tumor-destroying treatment (like focused radiation or heat ablation) can help people with certain gastrointestinal cancers—such as colorectal, small bowel, or pancreatic cancer—continue their current systemic therapy longer when only a few spots of cancer start to grow. About 300 adults with limited cancer progression will receive the ablation procedure alongside their ongoing treatment. The main goal is to see if this combination delays the need to switch or stop systemic therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Stereotactic ablative radiotherapy (SABR) or interventional radiology (IR) ablation therapy
- What this could lead to
- If successful, this approach could help people with certain GI cancers stay on their current systemic therapy longer by controlling limited tumor growth with targeted ablation.
- What could go wrong
- This is a mid-stage trial, so results are not yet proven. Ablation procedures carry risks like bleeding or infection, and the benefit may not apply to all cancer types or stages.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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University of California, Davis Comprehensive Cancer Center
RECRUITINGSacramento, California, 95817, United States
Contact Email: •••••@•••••
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