Zapping spreading tumors could extend life on current cancer drugs
NCT ID NCT06101277
First seen Jul 02, 2026 · Last updated Jul 02, 2026
Summary
This study tests whether adding a targeted, tumor-destroying treatment (like focused radiation or heat ablation) can help people with certain gastrointestinal cancers—such as colorectal, small bowel, or pancreatic cancer—continue their current systemic therapy longer when only a few spots of cancer start to grow. About 300 adults with limited cancer progression will receive the ablation procedure alongside their ongoing treatment. The main goal is to see if this combination delays the need to switch or stop systemic therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Stereotactic ablative radiotherapy (SABR) or interventional radiology (IR) ablation therapy
What this could lead to
If successful, this approach could help people with certain GI cancers stay on their current systemic therapy longer by controlling limited tumor growth with targeted ablation.
What could go wrong
This is a mid-stage trial, so results are not yet proven. Ablation procedures carry risks like bleeding or infection, and the benefit may not apply to all cancer types or stages.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Contacts and locations
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Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of California, Davis Comprehensive Cancer Center
RECRUITINGSacramento, California, 95817, United States
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••