New gene therapy offers hope for advanced cancers
NCT ID NCT04091295
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This expanded access program provides DNG64-CAR-V, a gene therapy, to patients with advanced pancreatic cancer, sarcoma, or breast cancer who have exhausted standard treatments. The therapy is given intravenously or directly into tumors, alone or with other cancer drugs. Early studies suggest it may stabilize or shrink tumors without severe side effects like bone marrow suppression.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
DNG64-CAR-V (a gene therapy vector that targets cancer cells)
What this could lead to
If it works, this could provide a new treatment option for people with advanced cancers that have not responded to standard therapies.
What could go wrong
This is an expanded access program, not a controlled trial, so results are uncertain. Tumors may appear to grow before shrinking (pseudoprogression), and not all patients will benefit.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Sarcoma Oncology Research Center, LLC
AVAILABLESanta Monica, California, 90403, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••