Can a Pre-Surgery drug stop dangerous pancreatic leaks?

NCT ID NCT06807437

Recruiting now Prevention Sponsor: SWOG Cancer Research Network Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated Apr 25, 2026 · Updated 27 times

Summary

This study tests whether giving the drug lanreotide before pancreatic surgery can prevent a common complication called a pancreatic fistula—a leak of digestive fluids that can cause infection. About 274 people with pancreatic cancer or precancerous lesions will be randomly assigned to receive either lanreotide or a placebo before their surgery. The goal is to see if the drug reduces the chance of developing a fistula after the pancreas is partially removed.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

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Locations

Atrium Health Cabarrus/LCI-Concord
SUSPENDED

Concord, North Carolina, 28025, United States
BJC Outpatient Center at Sunset Hills
RECRUITING

Sunset Hills, Missouri, 63127, United States

Contact

Contact Phone: •••-•••-••••
Banner MD Anderson Cancer Center
SUSPENDED

Gilbert, Arizona, 85234, United States
Baptist Memorial Hospital and Cancer Center-Memphis
SUSPENDED

Memphis, Tennessee, 38120, United States
Bronson Battle Creek
SUSPENDED

Battle Creek, Michigan, 49017, United States
Cancer and Hematology Centers of Western Michigan - Norton Shores
SUSPENDED

Norton Shores, Michigan, 49444, United States
Carilion Roanoke Memorial Hospital
SUSPENDED

Roanoke, Virginia, 24033, United States
Carolinas Medical Center/Levine Cancer Institute
SUSPENDED

Charlotte, North Carolina, 28203, United States
Christiana Care - Union Hospital
SUSPENDED

Elkton, Maryland, 21921, United States
Christiana Care Health System-Christiana Hospital
SUSPENDED

Newark, Delaware, 19718, United States
Christiana Care Health System-Concord Health Center
SUSPENDED

Chadds Ford, Pennsylvania, 19317, United States
Christiana Care Health System-Wilmington Hospital
SUSPENDED

Wilmington, Delaware, 19801, United States
City of Hope Comprehensive Cancer Center
SUSPENDED

Duarte, California, 91010, United States
Corewell Health Grand Rapids Hospitals - Butterworth Hospital
SUSPENDED

Grand Rapids, Michigan, 49503, United States
Corewell Health Grand Rapids Hospitals - Helen DeVos Children's Hospital
SUSPENDED

Grand Rapids, Michigan, 49503, United States
Corewell Health Lakeland Hospitals - Marie Yeager Cancer Center
SUSPENDED

Saint Joseph, Michigan, 49085, United States
Corewell Health Lakeland Hospitals - Niles Hospital
SUSPENDED

Niles, Michigan, 49120, United States
Corewell Health Lakeland Hospitals - Saint Joseph Hospital
SUSPENDED

Saint Joseph, Michigan, 49085, United States
Corewell Health Reed City Hospital
SUSPENDED

Reed City, Michigan, 49677, United States
Duluth Clinic Ashland
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Ashland, Wisconsin, 54806, United States
Emory Johns Creek Hospital
SUSPENDED

Johns Creek, Georgia, 30097, United States
Emory Saint Joseph's Hospital
SUSPENDED

Atlanta, Georgia, 30342, United States
Emory University Hospital Midtown
SUSPENDED

Atlanta, Georgia, 30308, United States
Emory University Hospital/Winship Cancer Institute
SUSPENDED

Atlanta, Georgia, 30322, United States
Essentia Health - Baxter Clinic
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Baxter, Minnesota, 56425, United States
Essentia Health - Deer River Clinic
SUSPENDED

Deer River, Minnesota, 56636, United States
Essentia Health - Ely Clinic
SUSPENDED

Ely, Minnesota, 55731, United States
Essentia Health - Fosston
SUSPENDED

Fosston, Minnesota, 56542, United States
Essentia Health - International Falls Clinic
SUSPENDED

International Falls, Minnesota, 56649, United States
Essentia Health - Jamestown Clinic
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Jamestown, North Dakota, 58401, United States
Essentia Health - Moose Lake Clinic
SUSPENDED

Moose Lake, Minnesota, 55767, United States
Essentia Health - Park Rapids
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Park Rapids, Minnesota, 56470, United States
Essentia Health - Saint Joseph's Crosslake Clinic
SUSPENDED

Crosslake, Minnesota, 56442, United States
Essentia Health - Saint Joseph's Pequot Lakes Clinic
SUSPENDED

Pequot Lakes, Minnesota, 56472, United States
Essentia Health - Saint Joseph's Pine River Clinic
SUSPENDED

Pine River, Minnesota, 56474, United States
Essentia Health - Saint Joseph's Staples Clinic
SUSPENDED

Staples, Minnesota, 56479, United States
Essentia Health Cancer Center
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Duluth, Minnesota, 55805, United States
Essentia Health Cancer Center-South University Clinic
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Fargo, North Dakota, 58103, United States
Essentia Health Hibbing Clinic
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Hibbing, Minnesota, 55746, United States
Essentia Health Saint Joseph's Medical Center
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Brainerd, Minnesota, 56401, United States
Essentia Health Saint Mary's - Detroit Lakes Clinic
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Detroit Lakes, Minnesota, 56501, United States
Essentia Health Saint Mary's Hospital - Superior
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Superior, Wisconsin, 54880, United States
Essentia Health Saint Mary's Medical Center
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Duluth, Minnesota, 55805, United States
Essentia Health Sandstone
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Sandstone, Minnesota, 55072, United States
Essentia Health Virginia Clinic
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Virginia, Minnesota, 55792, United States
Essentia Health-Hayward Clinic
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Hayward, Wisconsin, 54843, United States
Essentia Health-Spooner Clinic
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Spooner, Wisconsin, 54801, United States
Fred Hutchinson Cancer Center
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Seattle, Washington, 98109, United States
Geisinger Wyoming Valley/Henry Cancer Center
SUSPENDED

Wilkes-Barre, Pennsylvania, 18711, United States
Grady Health System
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Atlanta, Georgia, 30303, United States
Gulf Health Hospitals Inc/Infirmary Cancer Care - Malbis
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Daphne, Alabama, 36526, United States
Gulf Health Hospitals Inc/Infirmary Cancer Care - Saraland
SUSPENDED

Saraland, Alabama, 36571, United States
Helen F Graham Cancer Center
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Newark, Delaware, 19713, United States
Indiana University/Melvin and Bren Simon Cancer Center
SUSPENDED

Indianapolis, Indiana, 46202, United States
Marshfield Medical Center-Marshfield
RECRUITING

Marshfield, Wisconsin, 54449, United States

Contact

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Medical Oncology Hematology Consultants PA
SUSPENDED

Newark, Delaware, 19713, United States
Miller-Dwan Hospital
SUSPENDED

Duluth, Minnesota, 55805, United States
Missouri Baptist Medical Center
RECRUITING

St Louis, Missouri, 63131, United States

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Missouri Baptist Sullivan Hospital
RECRUITING

Sullivan, Missouri, 63080, United States

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Mobile Infirmary Medical Center
SUSPENDED

Mobile, Alabama, 36607, United States
Moffitt Cancer Center
SUSPENDED

Tampa, Florida, 33612, United States
Moffitt Cancer Center - McKinley Campus
RECRUITING

Tampa, Florida, 33612, United States

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Moffitt Cancer Center at SouthShore
SUSPENDED

Ruskin, Florida, 33570, United States
Moffitt Cancer Center at Wesley Chapel
SUSPENDED

Wesley Chapel, Florida, 33544, United States
Moffitt Cancer Center-International Plaza
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Tampa, Florida, 33607, United States
Northwest Wisconsin Cancer Center
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Ashland, Wisconsin, 54806, United States
Northwestern Medicine Cancer Center Delnor
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Geneva, Illinois, 60134, United States
Northwestern Medicine Cancer Center Warrenville
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Warrenville, Illinois, 60555, United States
Northwestern Medicine Oak Brook
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Oak Brook, Illinois, 60523, United States
Northwestern Medicine Orland Park
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Orland Park, Illinois, 60462, United States
Northwestern University
RECRUITING

Chicago, Illinois, 60611, United States

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Ohio State University Comprehensive Cancer Center
SUSPENDED

Columbus, Ohio, 43210, United States
Parkland Health Center - Farmington
RECRUITING

Farmington, Missouri, 63640, United States

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ProHealth D N Greenwald Center
SUSPENDED

Mukwonago, Wisconsin, 53149, United States
ProHealth Oconomowoc Memorial Hospital
SUSPENDED

Oconomowoc, Wisconsin, 53066, United States
ProHealth Waukesha Memorial Hospital
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Waukesha, Wisconsin, 53188, United States
Renown Regional Medical Center
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Reno, Nevada, 89502, United States
Riverwood Healthcare Center
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Aitkin, Minnesota, 56431, United States
Rutgers Cancer Institute of New Jersey
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New Brunswick, New Jersey, 08903, United States
Saint Barnabas Medical Center
SUSPENDED

Livingston, New Jersey, 07039, United States
Saint Luke's Cancer Center - Allentown
RECRUITING

Allentown, Pennsylvania, 18104, United States

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Saint Luke's Hospital - Monroe Campus
RECRUITING

Stroudsburg, Pennsylvania, 18360, United States

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Saint Luke's Hospital - Upper Bucks Campus
RECRUITING

Quakertown, Pennsylvania, 18951, United States

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Saint Luke's Hospital-Anderson Campus
RECRUITING

Easton, Pennsylvania, 18045, United States

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Saint Luke's University Hospital-Bethlehem Campus
RECRUITING

Bethlehem, Pennsylvania, 18015, United States

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Sainte Genevieve County Memorial Hospital
RECRUITING

Sainte Genevieve, Missouri, 63670, United States

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Sanford Broadway Medical Center
SUSPENDED

Fargo, North Dakota, 58122, United States
Sanford Cancer Center Oncology Clinic
SUSPENDED

Sioux Falls, South Dakota, 57104, United States
Sanford Roger Maris Cancer Center
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Fargo, North Dakota, 58122, United States
Sanford USD Medical Center - Sioux Falls
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Sioux Falls, South Dakota, 57117-5134, United States
State University of New York Upstate Medical University
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Syracuse, New York, 13210, United States
Tamarack Health Hayward Medical Center
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Hayward, Wisconsin, 54843, United States
Thomas Hospital
SUSPENDED

Fairhope, Alabama, 36532, United States
Trinity Health Grand Rapids Hospital
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Grand Rapids, Michigan, 49503, United States
Trinity Health Muskegon Hospital
SUSPENDED

Muskegon, Michigan, 49444, United States
UC San Diego Medical Center - Hillcrest
SUSPENDED

San Diego, California, 92103, United States
UC San Diego Moores Cancer Center
RECRUITING

La Jolla, California, 92093, United States

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USC / Norris Comprehensive Cancer Center
SUSPENDED

Los Angeles, California, 90033, United States
UW Cancer Center at ProHealth Care
SUSPENDED

Waukesha, Wisconsin, 53188, United States
University Medical Center New Orleans
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New Orleans, Louisiana, 70112, United States
University of Alabama at Birmingham Cancer Center
SUSPENDED

Birmingham, Alabama, 35233, United States
University of Cincinnati Cancer Center-UC Medical Center
SUSPENDED

Cincinnati, Ohio, 45219, United States
University of Cincinnati Cancer Center-West Chester
SUSPENDED

West Chester, Ohio, 45069, United States
University of Illinois
RECRUITING

Chicago, Illinois, 60612, United States

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University of Kentucky/Markey Cancer Center
RECRUITING

Lexington, Kentucky, 40536, United States

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University of Michigan Health - West
SUSPENDED

Wyoming, Michigan, 49519, United States
University of Michigan Rogel Cancer Center
SUSPENDED

Ann Arbor, Michigan, 48109, United States
University of Nebraska Medical Center
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Omaha, Nebraska, 68198, United States
University of New Mexico Cancer Center
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Albuquerque, New Mexico, 87106, United States
University of Rochester
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Rochester, New York, 14642, United States
University of Tennessee - Knoxville
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Knoxville, Tennessee, 37920, United States
University of Vermont Medical Center
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Burlington, Vermont, 05401, United States
University of Vermont and State Agricultural College
SUSPENDED

Burlington, Vermont, 05405, United States
University of Washington Medical Center - Montlake
SUSPENDED

Seattle, Washington, 98195, United States
VCU Massey Cancer Center at Stony Point
RECRUITING

Richmond, Virginia, 23235, United States

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VCU Massey Comprehensive Cancer Center
RECRUITING

Richmond, Virginia, 23298, United States

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Valley Health / Winchester Medical Center
SUSPENDED

Winchester, Virginia, 22601, United States
Veterans Affairs Loma Linda Healthcare System
SUSPENDED

Loma Linda, California, 92357, United States

Conditions

Explore the condition pages connected to this study.

PANCREATIC CARCINOMA PANCREATIC NEOPLASM