Surgical glue may seal pancreas after cancer surgery, cutting dangerous leaks
NCT ID NCT07155525
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase 3 trial tests whether adding a surgical glue called N-butyl-2-cyanoacrylate to standard pancreatic surgery can prevent postoperative pancreatic fistula—a common and serious leak of digestive fluids. About 194 patients with soft pancreas tissue undergoing tumor removal will be randomly assigned to receive either standard surgery or surgery plus glue. The main goal is to see if the glue reduces leak rates within 30 days after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
N-butyl-2-cyanoacrylate (surgical glue, brand name Glubran® 2)
What this could lead to
If it works, this could reduce the risk of pancreatic leaks after surgery, leading to fewer complications and shorter hospital stays for patients with soft pancreas tissue.
What could go wrong
This is a single-center trial with 194 patients, so results may not apply broadly. The glue could cause inflammation or fail to prevent leaks, and surgery risks like infection or bleeding remain.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for PANCREATIC CANCER are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Liver and GIT hospital , Minia University
RECRUITINGMinya, Minya Governorate, 61519, Egypt
Contact Phone: •••-•••-•••• Email: •••••@•••••