Surgical glue may seal pancreas after cancer surgery, cutting dangerous leaks
NCT ID NCT07155525
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This phase 3 trial tests whether adding a surgical glue called N-butyl-2-cyanoacrylate to standard pancreatic surgery can prevent postoperative pancreatic fistula—a common and serious leak of digestive fluids. About 194 patients with soft pancreas tissue undergoing tumor removal will be randomly assigned to receive either standard surgery or surgery plus glue. The main goal is to see if the glue reduces leak rates within 30 days after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- N-butyl-2-cyanoacrylate (surgical glue, brand name Glubran® 2)
- What this could lead to
- If it works, this could reduce the risk of pancreatic leaks after surgery, leading to fewer complications and shorter hospital stays for patients with soft pancreas tissue.
- What could go wrong
- This is a single-center trial with 194 patients, so results may not apply broadly. The glue could cause inflammation or fail to prevent leaks, and surgery risks like infection or bleeding remain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Liver and GIT hospital , Minia University
RECRUITINGMinya, Minya Governorate, 61519, Egypt
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Other studies related to the condition(s) this trial covers.
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