Can a family registry crack the code of inherited pancreatic cancer?

NCT ID NCT02886247

Recruiting now Knowledge-focused Sponsor: Johns Hopkins University Source: ClinicalTrials.gov ↗

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This study is a large registry that collects health and genetic information from people with a personal or family history of pancreatic tumors. The goal is to find the genes and other factors that cause pancreatic cancer to run in some families. By studying thousands of participants, researchers hope to identify new inherited risk genes and better understand why up to 10% of patients have a close relative with the disease.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this registry could identify new genes that raise pancreatic cancer risk in families, potentially leading to earlier detection and better screening for at-risk relatives.
What could go wrong: As a registry study, it does not test a treatment, so it cannot directly change outcomes. Findings may take years to translate into clinical practice, and not all families will have a clear genetic cause identified.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hereditary sensory and autonomic neuropathy malignant pancreatic neoplasm pancreatic neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PANCREATIC CANCER, ATM, BRCA, HEREDITARY CANCER

Contacts and locations

Locations

Johns Hopkins Hospital
RECRUITING

Baltimore, Maryland, 21231, United States

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