New combo therapy aims to stop pancreatic cancer return after surgery
NCT ID NCT07632118
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial tests whether adding radiotherapy to standard chemotherapy after pancreatic cancer surgery can prevent the cancer from coming back. It enrolls 288 high-risk patients who have had surgery but still have factors like positive margins or lymph node involvement. Participants receive either chemotherapy alone or chemotherapy plus targeted radiation, and researchers track how long they stay cancer-free.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Radiotherapy plus gemcitabine and capecitabine chemotherapy
- What this could lead to
- If successful, this could establish a new standard treatment to reduce recurrence and improve survival for high-risk pancreatic cancer patients after surgery.
- What could go wrong
- This is a mid-stage trial with 288 participants, so results may not apply to all patients. Radiotherapy can cause side effects like fatigue and digestive issues, and the benefit over chemotherapy alone is not yet proven.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Tianjin medical university hospital and institute
RECRUITINGTianjin, Tianjin Municipality, 300060, China
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Other studies related to the condition(s) this trial covers.
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