Shunt surgery may reverse liver failure in some cirrhosis patients
NCT ID NCT07172035
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a procedure called TIPS, which creates a bypass in the liver, can help people with advanced cirrhosis achieve 'recompensation' — meaning the liver partially recovers and complications ease. Researchers will follow 250 patients for one year after TIPS to see how many meet recompensation criteria and what factors influence success. The goal is to improve survival and reduce the need for liver transplants.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Transjugular intrahepatic portosystemic shunt (TIPS) procedure
What this could lead to
If successful, this could show that TIPS helps some patients with advanced cirrhosis achieve liver recompensation, potentially reducing complications and improving survival.
What could go wrong
This is an early-stage observational study, not a randomized trial, so results may not prove cause and effect. TIPS also carries risks like liver function decline and brain fog (hepatic encephalopathy).
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Fujian Medical University Union Hospital
RECRUITINGFuzhou, China
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Huanggang Central Hospital
RECRUITINGHuanggang, China
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Jiangxi Provincial People's Hospital
RECRUITINGNanchang, China
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Jingzhou Central Hospital
RECRUITINGJingzhou, China
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Renmin Hospital of Wuhan University
RECRUITINGWuhan, China
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Second Xiangya Hospital, Central South University
RECRUITINGChangsha, China
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Shanxi Provincial People's Hospital
RECRUITINGTaiyuan, China
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Shengjing Hospital of China Medical University
RECRUITINGShenyang, China
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The First Affiliated Hospital of Nanjing Medical University
RECRUITINGNanjing, China
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The First Affiliated Hospital of Zhengzhou University
RECRUITINGZhengzhou, China
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The Third Xiangya Hospital of Central South University
RECRUITINGChangsha, China
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Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
RECRUITINGWuhan, China
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Xiangyang Central Hospital
RECRUITINGXiangyang, China
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Yichang Central People's Hospital
RECRUITINGYichang, China
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Zhongnan Hospital of Wuhan University
RECRUITINGWuhan, China