Artificial intelligence may help decide who gets a liver first

NCT ID NCT06723275

Recruiting now Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jul 29, 2026 · Last updated Jul 30, 2026 · Updated 1 time

Summary

This study tests whether artificial intelligence can more accurately predict which patients on the liver transplant waiting list are at highest risk of dying or becoming too sick for surgery. Researchers will follow 630 adults with severe liver disease or liver cancer across five European countries, collecting blood, urine, and tissue samples along with detailed health data. The goal is to validate new AI-based models that could eventually replace current scoring systems and improve how donor livers are allocated.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could lead to fairer and more accurate systems for allocating donor livers to the patients who need them most urgently.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly help participants. The AI models may not prove more accurate than current methods.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cholangitis, Sclerosing chronic liver failure cirrhosis of liver hepatocellular carcinoma primary biliary cholangitis primary sclerosing cholangitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DECOMPENSATED LIVER CIRRHOSIS HEPATO-CELLULAR CARCINOMA PRIMARY BILIARY CHOLANGITIS PRIMARY SCLEROSING CHOLANGITIS

Contacts and locations

Locations

Beaujon Hospital, Department of Hepatology
RECRUITING

Clichy, France, 92110, France
Center for Liver Tumors Leiden of the Leiden University Medical Center (LUMC)
NOT_YET_RECRUITING

Leiden, Netherlands, Netherlands
Department of Gastroenterology and Hepatology Universitair Ziekenhuis Gent
NOT_YET_RECRUITING

Ghent, Belgium, Belgium
Hospital Henri Mondor, Department of Hepatology
RECRUITING

Créteil, France, 94010, France
Hospital La Pitié Salpêtrière, Department of Hepato-gastro-enterology
RECRUITING

Paris, France, 75013, France
Italian National Transplant Center
NOT_YET_RECRUITING

Roma, Italy, Italy
St Eloi Hospital, Department of Hepato-gastro-enterology,
RECRUITING

Montpellier, France, 34295, France
Universitätsklinikum Schleswig - Holstein | UKSH · Transplantation Medicine
NOT_YET_RECRUITING

Kiel, Germany, Germany

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