PRIMARY SCLEROSING CHOLANGITIS
Clinical trials for PRIMARY SCLEROSING CHOLANGITIS explained in plain language.
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Could a vitamin B12 derivative help tame a rare liver disease?
Disease control Recruiting nowThis study is testing whether an oral medication called BRS201 can help control primary sclerosing cholangitis (PSC), a rare liver disease. For 8 weeks, 28 participants will take either the study drug or a placebo pill in a random order to see if it can normalize a key liver enzy…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE2 • Sponsor: Brigham and Women's Hospital • Aim: Disease control
Last updated Apr 01, 2026 14:43 UTC
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First human test for potential liver disease drug begins
Disease control Recruiting nowThis is an early-stage study to check the safety of a new drug called TAK-781. It will first be given to healthy volunteers to see how their bodies handle it. Then, a single dose will be given to a small group of people with a specific chronic liver disease called primary scleros…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE1 • Sponsor: Takeda • Aim: Disease control
Last updated Apr 01, 2026 14:41 UTC
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New drug tested to protect transplanted livers
Disease control Recruiting nowThis early-stage study is testing the safety of an investigational drug called siplizumab in patients with autoimmune liver disease who are receiving a liver transplant. The drug is given right after surgery to help prevent the body's immune system from attacking the new liver. U…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE1 • Sponsor: Elizabeth C. Verna • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Scientists launch deep dive to unlock mysteries of rare liver disease
Knowledge-focused Recruiting nowThis study aims to understand the biological causes of Primary Sclerosing Cholangitis (PSC), a rare and serious chronic liver disease. Researchers will collect extensive samples—like blood, stool, and tissue—and perform various tests on about 143 adult participants with PSC over …
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:35 UTC
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Scientists grow Mini-Livers from patient bile to crack disease code
Knowledge-focused Recruiting nowThis study aims to better understand Primary Sclerosing Cholangitis (PSC), a serious liver disease, and related cancers. Researchers will collect bile samples from 300 people with and without PSC during routine medical procedures. They will use these samples to grow tiny 3D liver…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Mayo clinic launches massive biobank to crack the code on rare liver diseases
Knowledge-focused Recruiting nowThis study is creating a large collection of blood, saliva, stool, and other samples from people with rare liver diseases and healthy volunteers. The goal is to help researchers better understand diseases like Primary Sclerosing Cholangitis (PSC) and Primary Biliary Cholangitis (…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:32 UTC
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Scientists probe common drug as clue to mysterious liver disease
Knowledge-focused Recruiting nowThis study aims to understand why patients develop a serious liver disease called Primary Sclerosing Cholangitis (PSC), which has no cure and often leads to cancer or transplant. Researchers will give 15 adult patients with PSC a common cholesterol-lowering drug (rosuvastatin) to…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: EARLY_PHASE1 • Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Scientists hunt for gut bacteria clues in liver disease
Knowledge-focused Recruiting nowThis study aims to understand the connection between gut bacteria and several chronic liver diseases. Researchers will compare blood and stool samples from 3,000 adult patients with conditions like autoimmune hepatitis and fatty liver disease to samples from their healthy househo…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: Chungnam National University Hospital • Aim: Knowledge-focused
Last updated Mar 23, 2026 15:16 UTC
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Scientists launch major hunt for clues in mysterious childhood liver disease
Knowledge-focused Recruiting nowThis study aims to better understand primary sclerosing cholangitis (PSC), a rare disease that scars the liver's bile ducts. Researchers will observe 1,000 children and young adults (ages 2-25) who already have PSC, collecting health information, images, and samples over time. Th…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Sponsor: Arbor Research Collaborative for Health • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC