New drug aims to shield transplanted livers from immune attack

NCT ID NCT06455280

First seen Jan 04, 2026 · Last updated May 16, 2026 · Updated 18 times

Summary

This early study tests whether siplizumab can safely prevent the immune system from attacking a new liver in people with autoimmune hepatitis or primary sclerosing cholangitis. Eight participants will receive two doses of the drug around the time of transplant and be monitored for one year. The main goal is to check for serious infections and other safety issues.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center/NewYork-Presbyterian Hospital

    RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

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