END STAGE LIVER DISEASE

This early study tests whether siplizumab can safely prevent the immune system from attacking a new liver in people with autoimmune hepatitis or primary sclerosing cholangitis. Eight participants will receive two doses of the drug around the time of transplant and be monitored fo…

This study is for adults with end-stage liver disease who are waiting for a liver transplant. It compares three approaches: a diet with protein spread evenly across meals plus exercise, a diet with protein mostly at one meal plus exercise, or standard advice. The goal is to see w…

This study tests a home-based program called LiverWatch for people with advanced liver disease (cirrhosis). Participants get a Fitbit, personalized nutrition advice, and weekly education. The goal is to see if this helps improve physical activity, diet, and overall well-being. Ab…

This study tests a new approach to help liver transplant recipients stop taking toxic anti-rejection drugs for good. Twelve adults who received a liver from a living donor at least one year ago will get a donor stem cell infusion after a mild radiation and antibody treatment. The…

This study looks at 60 adults waiting for a liver transplant to see how frailty, nutrition, and mental health affect their recovery. Participants will do simple physical tests and answer questions about their daily life and well-being. The goal is to find which patients may need …

This study is testing a web-based app that helps people waiting for a kidney or liver transplant share their story on social media to find a living donor. Researchers want to see if this approach brings in more potential donors and leads to more transplants. About 1,000 adults on…

This study looks at why some patients with end-stage liver disease are less likely to be placed on a transplant waiting list or receive a new liver. Researchers will track 100 patients to understand individual and social factors that create these differences. The goal is to use t…