Frailty test could predict who survives liver transplant waiting list

NCT ID NCT03228290

First seen Jul 14, 2026 · Last updated Jul 15, 2026 · Updated 1 time

Summary

This study follows 5000 adults with advanced liver disease to see how frailty — measured by grip strength, chair stands, and balance — relates to their outcomes before and after a liver transplant. Participants are tested at every clinic visit and for a year after transplant, then followed annually. The goal is to learn whether simple physical tests can help identify who is too frail for transplant or needs extra care.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this could help doctors better predict which liver transplant candidates are too frail for surgery and who might need extra support.
What could go wrong
This is an observational study, not a treatment trial, so it won't directly improve health. Results may not apply to all liver patients.

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Conditions

The condition(s) this trial relates to.

chronic liver failure End Stage Liver Disease Fibrosis Frailty

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Baylor Scott & White Health

    RECRUITING

    Dallas, Texas, 75246, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Columbia University

    RECRUITING

    New York, New York, 10032, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Duke University Medical Center

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Indiana University

    ACTIVE_NOT_RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Johns Hopkins

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • Loma Linda University

    COMPLETED

    Loma Linda, California, 92354, United States

  • Northwestern University

    RECRUITING

    Chicago, Illinois, 60611, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

  • University of Arkansas for Medical Sciences

    COMPLETED

    Little Rock, Arkansas, 72205, United States

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Michigan

    COMPLETED

    Ann Arbor, Michigan, 48109, United States

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15237, United States

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Washington

    RECRUITING

    Seattle, Washington, 98195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Email: •••••@•••••

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