Could a stem cell shot free liver transplant patients from a lifetime of pills?
NCT ID NCT07269041
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a donor stem cell infusion can retrain the immune system to accept a liver transplant without lifelong anti-rejection drugs. Twelve adults who had a liver transplant from a matched living donor at least one year ago will receive the infusion after a mild conditioning regimen. The goal is to see if they can safely stop all immunosuppressants within a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Donor stem cell infusion
- What this could lead to
- If successful, this could allow liver transplant recipients to stop taking lifelong immunosuppressive drugs, reducing serious side effects.
- What could go wrong
- This is an early, small study with only 12 participants. The conditioning regimen carries risks like infection or graft rejection, and the approach may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
UCLA Health 200 Medical Plaza
RECRUITINGLos Angeles, California, 90095, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could tiny molecules in breast milk shape a Baby's food tolerance?
- A new Anti-Rejection strategy may spare kidney function after liver transplant
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- Better crystal ball for liver crisis: new scores put to the test