Could a stem cell shot free liver transplant patients from a lifetime of pills?
NCT ID NCT07269041
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether a donor stem cell infusion can retrain the immune system to accept a liver transplant without lifelong anti-rejection drugs. Twelve adults who had a liver transplant from a matched living donor at least one year ago will receive the infusion after a mild conditioning regimen. The goal is to see if they can safely stop all immunosuppressants within a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Donor stem cell infusion
What this could lead to
If successful, this could allow liver transplant recipients to stop taking lifelong immunosuppressive drugs, reducing serious side effects.
What could go wrong
This is an early, small study with only 12 participants. The conditioning regimen carries risks like infection or graft rejection, and the approach may not work for everyone.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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UCLA Health 200 Medical Plaza
RECRUITINGLos Angeles, California, 90095, United States
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
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