END STAGE LIVER DISEASE
Clinical trials for END STAGE LIVER DISEASE explained in plain language.
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Machine perfusion may keep livers healthier for transplant
Disease control Not yet recruitingThis study compares two methods of preserving livers from deceased donors before transplant: a machine that pumps oxygenated cold fluid through the liver (hypothermic machine perfusion) versus the standard ice-cooled storage. Forty adult liver transplant patients will be randomly…
Matched conditions: END STAGE LIVER DISEASE
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:35 UTC
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New device could keep donor livers healthier before transplant
Disease control Not yet recruitingThis study tests a device that keeps donor livers cool and oxygenated before transplant, aiming to reduce early liver problems. About 215 first-time liver transplant patients will receive a liver preserved with this method. The goal is to see if it lowers the risk of early graft …
Matched conditions: END STAGE LIVER DISEASE
Phase: NA • Sponsor: XVIVO Perfusion • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Could your own fat cells protect your new liver?
Disease control Not yet recruitingThis study tests the safety of using a patient's own stem cells (taken from fat) to prevent bile duct complications after a living donor liver transplant. About 20 adults with end-stage liver disease will receive these cells during surgery. The goal is to see if this approach red…
Matched conditions: END STAGE LIVER DISEASE
Phase: PHASE1 • Sponsor: Mayo Clinic • Aim: Disease control
Last updated Jun 27, 2026 12:04 UTC
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Could dumping first blood after liver transplant save lives?
Knowledge-focused Not yet recruitingThis study looks at a simple idea: during a liver transplant, the first blood that flows into the new liver may contain harmful substances. By discarding that blood before connecting the liver to the patient's circulation, doctors hope to reduce heart, kidney, and liver problems.…
Matched conditions: END STAGE LIVER DISEASE
Phase: NA • Sponsor: University of Sao Paulo General Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:05 UTC
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Massive french study to reveal best way to harvest donor livers
Knowledge-focused Not yet recruitingThis large French study will follow 1,810 adults receiving their first liver transplant to see if the way the donor liver is removed affects outcomes. The main focus is on avoiding artery and bile duct complications for three years after transplant. The goal is to identify the be…
Matched conditions: END STAGE LIVER DISEASE
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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New study aims to sharpen predictions for liver transplant success
Knowledge-focused Not yet recruitingThis study will analyze data from 3,000 living liver donors and their recipients to create a more accurate prediction model for early graft failure after living donor liver transplantation. Researchers will also test how well existing prediction models work. The goal is to give d…
Matched conditions: END STAGE LIVER DISEASE
Sponsor: Erasmus Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC