New device could keep donor livers healthier before transplant

NCT ID NCT06916325

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests a device that keeps donor livers cool and oxygenated before transplant, aiming to reduce early liver problems. About 215 first-time liver transplant patients will receive a liver preserved with this method. The goal is to see if it lowers the risk of early graft dysfunction and improves overall survival.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
dual hypothermic oxygenated perfusion (DHOPE) using the Liver Assist device
What this could lead to
If successful, this could make more donor livers available for transplant and reduce early liver damage after surgery.
What could go wrong
This is an early-stage study without a control group, so results may not prove the device is better than standard preservation. Risks include potential device-related complications or no improvement in outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

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