New PSC drug enters early safety testing in humans

NCT ID NCT07229911

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage study tests whether the experimental drug TAK-781 is safe and tolerable in healthy volunteers and in people with primary sclerosing cholangitis (PSC), a chronic liver disease. The study also looks at how the body processes the drug. About 134 participants will be involved, and the study lasts up to 36 weeks. This is not a cure; it aims to gather safety data for future research.

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Conditions

The condition(s) this trial relates to.

Cholangitis, Sclerosing primary sclerosing cholangitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • ICON

    RECRUITING

    Salt Lake City, Utah, 84124, United States

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