New study tracks rare liver disease in kids to uncover clues

NCT ID NCT04181138

Recruiting now Knowledge-focused Sponsor: Arbor Research Collaborative for Health Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 15, 2026 · Updated 3 times

Summary

This study follows 1,000 children with primary sclerosing cholangitis (PSC), a rare liver disease that damages bile ducts. Researchers will collect medical data, DNA, and symptom reports over time to understand how the disease progresses and affects daily life. The goal is to identify factors that may speed up the disease, helping doctors better manage it in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this study could help doctors better understand PSC in children and identify factors that predict faster disease progression.
What could go wrong: This is an observational study, not a treatment trial, so it won't directly improve health. Results may take years and might not lead to new therapies.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cholangitis, Sclerosing liver disorder primary sclerosing cholangitis sclerosing cholangitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHOLANGITIS, SCLEROSING LIVER DISEASES PRIMARY SCLEROSING CHOLANGITIS

Contacts and locations

Locations

Ann & Robert H Lurie Children's Hospital
RECRUITING

Chicago, Illinois, 60611, United States
Children's Healthcare of Atlanta
RECRUITING

Atlanta, Georgia, 30322, United States
Children's Hospital Colorado
RECRUITING

Aurora, Colorado, 80045, United States
Children's Hospital of Los Angeles
RECRUITING

Los Angeles, California, 90027, United States
Cincinnati Children's Hospital Medical
RECRUITING

Cincinnati, Ohio, 45229, United States
Riley Hospital for Children
COMPLETED

Indianapolis, Indiana, 46202, United States
Seattle Children's Hospital
RECRUITING

Seattle, Washington, 98105, United States
Texas Children's Hospital (Baylor College of Medicine)
RECRUITING

Houston, Texas, 77030, United States
The Children's Hospital of Philadelphia
RECRUITING

Philadelphia, Pennsylvania, 19104, United States
The Hospital for Sick Children
COMPLETED

Toronto, Ontario, M5G 1X8, Canada
The University of Utah
RECRUITING

Salt Lake City, Utah, 84113, United States
UPMC Children's Hospital of Pittsburgh
COMPLETED

Pittsburgh, Pennsylvania, 15224, United States

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