Gene hunt for mysterious adult liver disease
NCT ID NCT07317193
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study is using advanced whole-genome sequencing to find hidden genetic causes of cholestatic liver disease in adults whose condition remains unexplained after standard tests. Researchers will compare the DNA of 60 affected adults to a large group of healthy controls. The goal is to improve diagnosis and understanding of these rare liver disorders.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to better genetic testing for adults with unexplained liver disease, helping doctors diagnose and manage the condition more effectively.
- What could go wrong
- This is an early-stage observational study with only 60 participants, so findings may not apply to everyone. Genetic sequencing may not find a cause for many patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico - Istituto di Ricovero e Cura a Carattere Scientifico di natura pubblica
RECRUITINGMilan, Milano, 20122, Italy
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