PRIMARY SCLEROSING CHOLANGITIS
Clinical trials for PRIMARY SCLEROSING CHOLANGITIS explained in plain language.
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New drug trial targets rare liver disease
Disease control OngoingThis study is testing an investigational drug called CS0159 for people with Primary Sclerosing Cholangitis (PSC), a rare disease that scars the bile ducts in the liver. About 50 participants will be randomly assigned to receive either the drug or a placebo for 12 weeks, followed …
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE2 • Sponsor: Cascade Pharmaceuticals, Inc • Aim: Disease control
Last updated Mar 31, 2026 12:10 UTC
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New hope for rare liver disease as experimental drug enters Mid-Stage trial
Disease control OngoingThis study is testing a drug called elafibranor in adults with primary sclerosing cholangitis (PSC), a rare disease that scars and blocks the liver's bile ducts. The main goal is to check the drug's safety and side effects. Researchers will also measure if it improves key liver b…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE2 • Sponsor: Ipsen • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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Common cholesterol drug tested as potential lifeline for rare liver disease
Disease control OngoingThis large, late-stage study is testing whether a common cholesterol-lowering drug, simvastatin, can improve the long-term outlook for people with primary sclerosing cholangitis (PSC), a rare liver disease. About 570 adults with PSC will take either simvastatin or a placebo pill …
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE3 • Sponsor: Annika Bergquist • Aim: Disease control
Last updated Mar 27, 2026 12:40 UTC
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Could cutting out gluten ease serious liver and gut diseases?
Disease control OngoingThis study is testing whether following a gluten-free diet can help control symptoms and slow the progression of two related diseases: primary sclerosing cholangitis (a serious liver disease) and ulcerative colitis (a type of inflammatory bowel disease). Researchers will enroll 6…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: NA • Sponsor: Institute for Clinical and Experimental Medicine • Aim: Disease control
Last updated Mar 23, 2026 15:18 UTC
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New drug trial targets debilitating itch in liver disease
Symptom relief OngoingThis study is testing whether an investigational drug called volixibat can safely reduce the severe itching (pruritus) experienced by people with primary sclerosing cholangitis (PSC), a chronic liver disease. The trial involves 182 participants who will receive either the drug or…
Matched conditions: PRIMARY SCLEROSING CHOLANGITIS
Phase: PHASE2 • Sponsor: Mirum Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated Mar 27, 2026 12:41 UTC