Could a common cholesterol drug slow a rare liver disease?
NCT ID NCT04133792
First seen Sep 30, 2025 · Last updated May 10, 2026 · Updated 34 times
Summary
This study tests whether taking simvastatin daily for 5 years can improve survival and reduce serious complications like liver failure, cancer, or bleeding in people with primary sclerosing cholangitis (PSC). About 560 adults with PSC will receive either simvastatin or a placebo. The goal is to see if this drug can help control the disease and delay the need for a liver transplant.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Akademiska sjukhuset
Uppsala, 751 85, Sweden
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Danderyds sjukhus
Stockholm, 182 57, Sweden
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Karlstads centralsjukhus
Karlstad, 652 30, Sweden
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Karolinska University Hospital
Stockholm, 141 57, Sweden
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Karolinska University Hospital Solna
Stockholm, 171 64, Sweden
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Norrlands Universitetssjukhus
Umeå, Västerbotten County, 907 37, Sweden
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Sahlgrenska Universitetssjukhuset
Gothenburg, Västra Götaland County, 413 45, Sweden
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Sahlgrenska Universitetssjukhuset Östra
Gothenburg, 41685, Sweden
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Skaraborgs sjukhus
Lidköping, Sweden
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Skåne Universitetssjukhus
Malmö, Skåne County, 222 42, Sweden
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Universitetssjukhuset i Linköping
Linköping, Östergötland County, 581 85, Sweden
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Örebro Universitetssjukhus
Örebro, 701 85, Sweden
Conditions
Explore the condition pages connected to this study.