New drug trial targets rare liver disease

NCT ID NCT05896137

Summary

This study is testing an investigational drug called CS0159 for people with Primary Sclerosing Cholangitis (PSC), a rare disease that scars the bile ducts in the liver. About 50 participants will be randomly assigned to receive either the drug or a placebo for 12 weeks, followed by a longer open period. The main goals are to see if the drug is safe and if it can lower a key liver enzyme (ALP) that indicates disease activity.

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Contacts and locations

Locations

  • Beijing Friendship Hospital, Captail Medcial University

    Beijing, Beijing Municipality, 100050, China

  • Beijing YouAn Hostital, Captial Medical University

    Beijing, Beijing Municipality, 100069, China

  • Peking Union Medical College Hospital

    Beijing, Beijing Municipality, 100730, China

  • Qilu Hospital of Shandong University

    Jinan, Shandong, China

  • Renji Hospital, Shanghai Jiao Tong University School of Medicine

    Shanghai, Shanghai Municipality, 200120, China

  • Shaoyifu Hospital of Zhejiang University Medical

    Hangzhou, Zhejiang, 310000, China

  • The First Affiliated Hospital of USTC Anhui Provincial Hospital

    Hefei, Anhui, China

  • The First Affiliated Hospital,Zhejiang University School of Medicine

    Hangzhou, Zhejiang, China

  • The First Bethune Hospital of Jilin University

    Changchun, Jilin, China

  • The Seconed Xiangya Hospital of Central South University

    Changsha, Hunan, 410011, China

  • Wuhan Union Hospital of China

    Wuhan, Hubei, 430022, China

Conditions

Explore the condition pages connected to this study.