PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Clinical trials for PORTAL HYPERTENSION RELATED TO CIRRHOSIS explained in plain language.
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New combo therapy could transform care for liver patients with obesity
Disease control Recruiting nowThis study tests a two-step treatment for people with advanced liver disease (cirrhosis) and severe obesity. One group gets a procedure to lower liver pressure (TIPS) followed by weight-loss surgery, while the other gets standard medical care. The goal is to see if the combinatio…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: PHASE4 • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated May 17, 2026 05:50 UTC
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New stent graft aims to tame deadly liver complications
Disease control Recruiting nowThis study tests a special stent graft (LIVERTY TIPS) placed in the liver to help people with cirrhosis and high blood pressure in the portal vein. The goal is to keep the stent open and reduce serious complications like internal bleeding or fluid buildup. About 166 adults aged 1…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated May 17, 2026 05:34 UTC
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Can a common heart drug prevent deadly bleeding in liver disease?
Disease control Recruiting nowThis study tests whether the drug carvedilol can reduce high blood pressure in the liver's blood vessels, a common problem in people with cirrhosis. High pressure raises the risk of life-threatening bleeding. The trial will enroll 30 adults with cirrhosis and use a special ultras…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: University Hospital, Clermont-Ferrand • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Can a simple supplement boost muscle and survival in liver disease patients?
Disease control Recruiting nowThis study looks at people with cirrhosis (scarred liver) who also have severe muscle loss (sarcopenia) and need a procedure called TIPS to treat complications like bleeding. Half will get standard care, and half will also take branched-chain amino acid (BCAA) supplements for 6 m…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Spleen scan may spot hidden danger in liver patients
Diagnosis Recruiting nowThis study looks at whether a non-invasive ultrasound technique that measures spleen stiffness can accurately identify high blood pressure in the liver and risky enlarged veins (varices) in people with advanced chronic liver disease. Researchers will enroll 450 adults and compare…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated May 13, 2026 16:02 UTC
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New study aims to find best way to spot liver cancer early in cirrhosis patients
Knowledge-focused Recruiting nowThis study is looking at 600 adults with liver cirrhosis to see which imaging method—MRI or ultrasound—works better for finding liver cancer early. Researchers will also track body composition and other health changes over time. The goal is to improve how doctors monitor and pred…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Mattias Ekstedt • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC
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Liver clot clues: 1500-Patient study seeks answers
Knowledge-focused Recruiting nowThis study follows 1500 people with cirrhosis and varices who also have a blood clot in the portal vein (the main vein to the liver). Researchers will track who gets better and what factors help the clot dissolve over 1 to 5 years. The goal is to better understand the disease and…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC