PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Clinical trials for PORTAL HYPERTENSION RELATED TO CIRRHOSIS explained in plain language.
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New combo treatment aims to help patients with liver disease and obesity
Disease control Recruiting nowThis study tests whether a two-step procedure can help people with advanced liver disease and severe obesity. First, a TIPS procedure lowers pressure in the liver veins. Then, sleeve gastrectomy surgery helps with weight loss. The study compares this approach to standard medical …
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: PHASE4 • Sponsor: The Cleveland Clinic • Aim: Disease control
Last updated Jun 27, 2026 08:06 UTC
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New liver stent aims to tame deadly cirrhosis complications
Disease control Recruiting nowThis study tests a special stent called LIVERTY TIPS, placed in the liver to create a new pathway for blood flow in people with cirrhosis and high blood pressure in the liver. The goal is to see if it can keep the new channel open and reduce problems like bleeding or fluid buildu…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: C. R. Bard • Aim: Disease control
Last updated Jun 27, 2026 08:05 UTC
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Can amino acid supplements help reverse muscle wasting in liver disease patients?
Disease control Recruiting nowThis study looks at whether adding branched-chain amino acid (BCAA) supplements to a standard liver procedure (TIPS) can help reverse muscle loss (sarcopenia) in people with cirrhosis and high blood pressure in the liver. About 164 patients will be randomly assigned to receive ei…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Can a common heart drug prevent bleeding in cirrhosis?
Disease control Recruiting nowThis study tests whether carvedilol, a beta-blocker, can reduce high blood pressure in the liver's portal vein in people with cirrhosis. High pressure can lead to dangerous bleeding. Researchers will use an endoscopic ultrasound to measure pressure before and after one month of t…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: University Hospital, Clermont-Ferrand • Aim: Disease control
Last updated Jun 27, 2026 07:51 UTC
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Spleen scan could spare liver patients risky needle test
Diagnosis Recruiting nowThis study is testing whether a non-invasive ultrasound of the spleen can accurately detect dangerous vein swelling and high blood pressure in the liver. Researchers will enroll 450 adults with advanced chronic liver disease. If successful, this simple scan could replace the curr…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Jun 27, 2026 07:59 UTC
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New ultrasound technique could replace needle biopsy for liver patients
Knowledge-focused Recruiting nowThis study tests whether a special ultrasound done through an endoscope can measure how well beta-blockers are working in people with cirrhosis and high blood pressure in the liver. Twenty-four participants will get the ultrasound before and after three months of treatment with c…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Phase: NA • Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:01 UTC
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Tiny plastics, big trouble? new study probes microplastic impact on liver disease
Knowledge-focused Recruiting nowThis study will check for microplastics in liver tissue from 30 people with cirrhosis who are having surgery or a liver transplant. Researchers want to see if these tiny plastic particles are linked to worse liver damage, higher blood pressure in the liver, and heart problems. Th…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Post Graduate Institute of Medical Education and Research, Chandigarh • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:34 UTC
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Liver clot study seeks to predict recovery in 1,500 patients
Knowledge-focused Recruiting nowThis study looks at factors that help blood clots in the main liver vein dissolve in people with liver scarring (cirrhosis) and enlarged stomach veins. Researchers will follow 1,500 patients over time to see what influences clot recovery. The goal is to help doctors and patients …
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Shanghai Zhongshan Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Can a quicker MRI beat ultrasound for spotting liver cancer?
Knowledge-focused Recruiting nowThis study looks at 600 adults with liver cirrhosis to see if a shorter MRI scan works better than ultrasound for finding early liver cancer. Researchers will also track body composition and other health changes over time. The goal is to improve how doctors monitor and predict li…
Matched conditions: PORTAL HYPERTENSION RELATED TO CIRRHOSIS
Sponsor: Mattias Ekstedt • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC