Could your muscle mass change how chemo works?

NCT ID NCT02734069

Recruiting now Knowledge-focused Sponsor: Instituto Nacional de Cancerologia de Mexico Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how a person's fat-free mass (like muscle) affects the dose and side effects of the chemotherapy drug carboplatin in patients with advanced non-small cell lung cancer. Researchers will track 132 patients to see if body composition is linked to toxicity. The goal is to improve dosing accuracy and reduce harmful side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Carboplatin
What this could lead to: If successful, this could lead to more personalized chemotherapy dosing based on body composition, potentially reducing side effects.
What could go wrong: This is an observational study, not a treatment trial. It may not change practice if results are inconclusive or not widely applicable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

lung cancer lung neoplasm non-small cell lung carcinoma Sarcopenia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

LUNG CANCER SARCOPENIA TOXICITY

Contacts and locations

Locations

Instituto Nacional de Cancerologia
RECRUITING

Mexico City, 14080, Mexico

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