Instituto Nacional De Cancerologia De Mexico

This study tests whether adding a nitroglycerin patch (a heart medication) to standard radiation therapy can better shrink brain tumors in people with a specific type of lung cancer (EGFR-mutant non-small cell lung cancer) that has spread to the brain. About 74 adults will receiv…

This phase 3 study tests whether adding the diabetes drug metformin to standard targeted therapy (tyrosine kinase inhibitors) can help control advanced non-small cell lung cancer with EGFR mutations. About 312 adults with stage IIIB or IV lung cancer will receive either metformin…

This study is for people with advanced ALK-positive non-small cell lung cancer. It tests three different doses of the drug alectinib to see how the body processes each dose and which dose works best. The goal is to find the safest and most effective dose to control the cancer.

This study tests whether adding glutamine and a probiotic (Lactobacillus reuteri) to a bland diet can prevent diarrhea caused by targeted therapy (TKIs) in people with advanced EGFR-mutant non-small cell lung cancer. About 28 participants will either receive the supplemented diet…

This study tests whether using inhaled steroids before and during radiation therapy can lower the risk and severity of lung inflammation (pneumonitis) in people with advanced non-small cell lung cancer. About 72 participants will receive either the inhaled steroid or a placebo al…

This study looks at whether a pulmonary rehabilitation program can help people with advanced non-small-cell lung cancer maintain muscle mass, improve lung function, and reduce inflammation. About 94 participants will take part while receiving standard cancer treatments like chemo…

This study is creating a questionnaire to measure how closely lung cancer patients follow their respiratory rehabilitation program. About 281 Mexican adults with lung cancer will fill out the 56-question scale. The goal is to make sure the tool is accurate and reliable, so doctor…

This study is testing whether yearly low-dose CT scans can help find lung cancer early in 1,000 high-risk adults in Mexico. Participants are 50 or older and are heavy smokers, former smokers, or have been exposed to wood smoke. The goal is to see if this screening method can catc…

This study looks at how a person's muscle mass (fat-free mass) relates to side effects from standard chemotherapy (carboplatin/paclitaxel) in advanced non-small cell lung cancer. Researchers will track 132 participants to see if adjusting the chemo dose based on body composition …